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Of the 23 trials they identified, 12 were methodologically sound enough to include in their analysis. The analysis revealed that some statistically significant weight loss occurred, but the magnitude of the effect is small and the clinical relevance is uncertain. They also found that gastrointestinal adverse events were twice as likely in the hydroxycitric acid group as in the placebo group.
Chemicals Alloxan and quercetin dihydrate were purchased from Sigma Chemicals Co. Al-Yassin D, Ibrahim K.
The pharmacological effects of the roots of W.